The tissue form of chicken type VI collagen

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Isolation from bovine elastic tissues of collagen type VI and characterization of its form in vivo.

Foetal-bovine nuchal ligament and aorta, together with adult-bovine aorta and pregnant uterus, were extracted under dissociative conditions in the absence and in the presence of a reducing agent. A collagenous glycoprotein of Mr 140000 [designated component 140K(VI)], identified in these extracts as the major periodate/Schiff-positive component, was shown to be related to collagen type VI. Dige...

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In conclusion, we have provided experimental and theoretical evidence that the a-helical, coiledcoil domain of laminin is responsible for chain assembly and chain selectivity. None of the laminin chains appears to be designed for formation of homodimers, although these are common in many other fibrous proteins [ 111. Only selected heteroassociations are stable in laminin isoforms. The data on f...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 1987

ISSN: 0014-5793

DOI: 10.1016/0014-5793(87)81514-4